Scripts for TRUMP data analyses. Part II (HLA-related data): statistical analyses specific for hematopoietic stem cell transplantation
نویسندگان
چکیده
منابع مشابه
Hematopoietic Stem Cell Transplantation for Thalassemia
Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...
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The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
متن کاملhematopoietic stem cell transplantation for thalassemia
thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. for β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...
متن کاملStatistical analyses for round robin interaction data
This paper considers the analysis of round robin interaction data whereby individuals from a group of subjects interact with one another, producing a pair of outcomes, one for each individual. The authors provide an overview of the various analyses applied these types of data and extend the work in several directions. In particular, they provide a fully Bayesian analysis for such data, and use ...
متن کاملThe Advanced HLA Typing Strategies for Hematopoietic Stem Cell Transplantation
The occurrence of graft rejection and/or graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is largely depended on whether the re‐ cipient and the donor have matched HLA types. Under normal circumstances, the individu‐ al with completely matched HLA antigens can be the donor. However, due to the high level of HLA polymorphism, the major obstacl...
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ژورنال
عنوان ژورنال: International Journal of Hematology
سال: 2015
ISSN: 0925-5710,1865-3774
DOI: 10.1007/s12185-015-1907-9